Formaldehyde

Formaldehyde

SCHEMBL1662313

C=O.O=[Si](O)Oc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
SRC P12931 1/20 0.38
LTA4H P09960 2/20 0.38
TSHR P16473 1/20 0.38
ALOX15 P16050 2/20 0.37
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
CA4 P22748 1/20 0.35
NR1H2 P55055 1/20 0.34
BAX Q07812 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
SOS1 Q07889 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230788 0.95 LTA4H (0.41) CA1CA2CA9SRCLTA4H
Sulfuric Acid SCHEMBL17983512 0.88 CA1 (0.41) CA1CA2CA9SRCLTA4H
Formaldehyde SCHEMBL11761279 0.84 CYP1A2 (0.37) TSHRCYP2C9CYP2C19KMT2AMEN1
Trolamine SCHEMBL11401678 0.78 TSHR (0.39) LTA4HTSHRALOX15CYP2C19KMT2A
SCHEMBL11518177 0.78 KMT2A (0.43) CA1CA2CA9SRCCA5A
Formaldehyde SCHEMBL11518761 0.77 CYP3A4 (0.47) CA1CA2CA9CA5ACA5B
Crotonaldehyde SCHEMBL11515561 0.77 TRPA1 (0.38) CA4KMT2AALDH1A1TDP1PARP10
SCHEMBL896124 0.74 LTA4H (0.45) CA1CA2CA9SRCLTA4H
Furfural SCHEMBL11519394 0.73 ALDH1A1 (0.56) TSHRCYP2C9CYP2C19KMT2AMEN1
SCHEMBL9073856 0.71 ALDH1A1 (0.46) TSHRALDH1A1TDP1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8409403-B2 Production of amino lignin and amino lignin cellulose resins and adhesives BLOUNT DAVID H (US) 2013-04-02 US disclosed
US-20110098384-A1 Production of amino lignin and amino lignin cellulose resins and adhesives BLOUNT DAVID H 2011-04-28 US disclosed
US-4317752-A POLYURETHANE FOAMS; INSULATION; CONSTRUCTION MATERIALS BLOUNT DAVID H 1982-03-02 US disclosed
US-4280006-A Process for the production of polyisocyanate silicate plastics utilizing an alkali metal cellulose silicate condensation product BLOUNT DAVID H 1981-07-21 US disclosed
US-4262108-A FIREPROOF CONSTRUCTION MATERIALS, INSULATION BLOUNT DAVID H 1981-04-14 US disclosed
US-4242497-A Production of amino-silicate compounds, condensation resinous products BLOUNT DAVID H 1980-12-30 US disclosed
US-4185147-A Production of amino-silicate compounds, condensation resinous products and foam BLOUNT DAVID H 1980-01-22 US disclosed
US-4156060-A Process for the production of poly (urethane silicate) prepolymers and cellular solid reaction products utilizing phenol silicate compounds and resinous products BLOUNT DAVID H 1979-05-22 US disclosed
US-4125703-A Process for the production of phenol silicate compounds and their condensation products BLOUNT DAVID H 1978-11-14 US disclosed
US-4032511-A PROCESS FOR THE PRODUCTION OF PHENOL SILICATE COMPOUNDS AND THEIR CONDENSATION PRODUCTS BLOUNT DAVID H 1977-06-28 US disclosed