Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624024 | 0.86 | SLC6A4 (0.48) | MTNR1BMTNR1ASIGMAR1KDM2BHRH3 | |
| SCHEMBL17993845 | 0.82 | SIGMAR1 (0.56) | MTNR1BSIGMAR1GRIN2BGRIN1DRD1 | |
| SCHEMBL18033544 | 0.82 | SLC6A2 (0.37) | SIGMAR1GRIN2BGRIN1HRH3DRD1 | |
| SCHEMBL16624030 | 0.78 | SLC6A4 (0.48) | KDM2BGRIN2BGRIN1HRH3 | |
| SCHEMBL15088517 | 0.76 | HRH3 (0.61) | HRH3DRD1DRD2DRD5DRD3 | |
| SCHEMBL326892 | 0.75 | MTNR1A (0.54) | MTNR1BMTNR1ASIGMAR1DRD2DRD3 | |
| SCHEMBL4320078 | 0.74 | HRH3 (0.59) | SIGMAR1HRH3DRD1DRD2DRD5 | |
| SCHEMBL13521646 | 0.74 | DRD1 (0.57) | HRH3DRD1DRD2DRD5DRD3 | |
| SCHEMBL29557542 | 0.74 | DRD1 (0.57) | HRH3DRD1DRD2DRD5DRD3 | |
| SCHEMBL16624050 | 0.74 | ACACB (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |