Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18034955 | 0.85 | KDM4E (0.59) | KIF11TRPV1MAPK10RIPK1KDM4E | |
| SCHEMBL17993837 | 0.82 | ADRA1A (0.45) | TRPV1KDM4EMCHR1 | |
| SCHEMBL17993835 | 0.81 | KDM4E (0.46) | TRPV1KDM4E | |
| SCHEMBL16624295 | 0.80 | MEN1 (0.45) | TRPV1MAPK10RIPK1KDM4EMCHR1 | |
| SCHEMBL18033535 | 0.80 | KDM4E (0.44) | TRPV1KDM4EMCHR1MAPT | |
| SCHEMBL5378477 | 0.79 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL2190132 | 0.77 | CHRNA7 (0.59) | KIF11MAPK10RIPK1ALDH1A1KDM4E | |
| SCHEMBL16624099 | 0.77 | HTR7 (0.58) | TRPV1ALDH1A1KDM4EMAPT | |
| SCHEMBL8261111 | 0.76 | KDM4E (0.69) | TRPV1KDM4E | |
| SCHEMBL16624301 | 0.74 | BAZ2B (0.54) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053917-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015050212-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | 日産化学工業株式会社 | 2015-04-09 | — | — | WO | disclosed |