Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 5/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15462033 | 0.94 | KMT2A (0.51) | KMT2AATMTGM2HTR6EPHX1 | |
| SCHEMBL1618982 | 0.92 | KMT2A (0.49) | KMT2AATMTGM2 | |
| SCHEMBL15462046 | 0.81 | MAPT (0.48) | KMT2ATGM2EPHX2HDAC1HSD11B1 | |
| SCHEMBL15462017 | 0.80 | MAPT (0.51) | KMT2AATMTGM2 | |
| SCHEMBL1619009 | 0.78 | WDR5 (0.52) | KMT2A | |
| SCHEMBL1619036 | 0.77 | KMT2A (0.59) | KMT2AATMTGM2HTR6EPHX1 | |
| SCHEMBL15462044 | 0.76 | CHRM4 (0.45) | KMT2AHDAC1MMP2MMP13 | |
| SCHEMBL1662259 | 0.74 | ALDH1A1 (0.52) | KMT2AHDAC1MMP2MMP13 | |
| SCHEMBL25531 | 0.74 | KMT2A (0.88) | KMT2AATMTGM2HTR6EPHX1 | |
| SCHEMBL29437927 | 0.74 | KMT2A (0.88) | KMT2AATMTGM2HTR6EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088754-A1 | SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | EMELEN KRISTOF VAN (BE) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088754-A1 | SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE | HDAC3, HDAC1, HDAC11 | KMT2A 28/4885ATM 2606/4885TGM2 1368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.