SCHEMBL16624677

SCHEMBL16624677

CCCc1nc(C(C)(C)O)c(C(=O)OCc2oc(=O)oc2C)n1Cc1ccc(-c2ccccc2-c2cn[nH]n2)cc1

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 10/20 0.79
AGTR1 P30556 9/20 0.79
ABCC3 O15438 1/20 0.79
ABCC4 O15439 1/20 0.79
ABCB11 O95342 1/20 0.79
CYP3A4 P08684 1/20 0.79
PDE4D Q08499 1/20 0.79
PDE3A Q14432 1/20 0.79
SLCO1B3 Q9NPD5 1/20 0.79
TDP1 Q9NUW8 1/20 0.79
SLCO1B1 Q9Y6L6 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Olmesartan Medoxomil SCHEMBL28341316 0.88 AGTR1 (1.00) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL29087653 0.88 AGTR1 (1.00) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL16403 0.88 AGTR1 (1.00) AGTR2AGTR1ABCC3ABCC4ABCB11
SCHEMBL1640019 0.88 AGTR2 (0.79) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28547990 0.88 AGTR1 (0.99) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28754180 0.88 AGTR1 (0.99) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL4132257 0.88 AGTR1 (0.99) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL27934840 0.88 AGTR1 (0.99) AGTR2AGTR1ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL27822335 0.88 AGTR1 (0.99) AGTR2AGTR1ABCC3ABCC4ABCB11
SCHEMBL7302141 0.87 AGTR1 (0.76) AGTR2AGTR1ABCC3ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150098993-A1 COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS AND METHOD OF TREATING INFLAMMATORY DISEASES CELLWORKS GROUP, INC. 2015-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150098993-A1 COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS AND METHOD OF TREATING INFLAMMATORY DISEASES TNF, C5, IL5 AGTR2 2567/4885AGTR1 2464/4885ABCC3 1689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.