Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 6/20 | 0.36 |
| ▸ | AKT2 | P31751 | 4/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25277524 | 0.88 | AKT1 (0.42) | SLC15A1AKT1AKT2AKT3CSNK1A1 | |
| SCHEMBL25277525 | 0.88 | AKT1 (0.42) | SLC15A1AKT1AKT2AKT3CSNK1A1 | |
| SCHEMBL16624828 | 0.86 | GABRP (0.34) | SLC15A1AKT1AKT2AKT3CSNK1A1 | |
| SCHEMBL16624821 | 0.85 | HTT (0.34) | AKT1AKT2AKT3PDGFRBP2RY12 | |
| SCHEMBL16616178 | 0.83 | MEN1 (0.47) | MEN1MAPTKMT2APOLBCNR1 | |
| SCHEMBL29165621 | 0.73 | MEN1 (0.49) | MEN1MAPTKMT2APOLBCNR1 | |
| SCHEMBL29165557 | 0.72 | MTNR1B (0.37) | AKT1AKT2AKT3PDGFRBP2RY12 | |
| SCHEMBL29165554 | 0.72 | MTNR1B (0.37) | AKT1AKT2AKT3PDGFRBP2RY12 | |
| SCHEMBL16773677 | 0.70 | AURKA (0.41) | AKT1AKT2AKT3MEN1KMT2A | |
| SCHEMBL30776945 | 0.66 | KIT (0.47) | MEN1MAPTTSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309204-B2 | Process for making hydroxylated cyclopentylpyrimidine compounds | ARRAY BIOPHARMA INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150099881-A1 | PROCESS FOR MAKING HYDROXYLATED CYCLOPENTYLPYRIMIDINE COMPOUNDS | GENETECH, INC. (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099881-A1 | PROCESS FOR MAKING HYDROXYLATED CYCLOPENTYLPYRIMIDINE COMPOUNDS | PIK3CA, DHPS, PIK3CD | SLC15A1 3501/4885AKT1 24/4885AKT2 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.