Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10526733 | 0.98 | KMT2A (0.62) | KMT2AMEN1RECQLRAB9APABPC1 | |
| Bromide SCHEMBL3844583 | 0.98 | KMT2A (0.67) | KMT2AMEN1RECQLRAB9APABPC1 | |
| SCHEMBL10531142 | 0.86 | POLB (0.64) | KMT2AMEN1RECQLRAB9APABPC1 | |
| Bromide SCHEMBL10528569 | 0.84 | POLB (0.67) | KMT2AMEN1RECQLPABPC1ATM | |
| SCHEMBL20527639 | 0.84 | PABPC1 (0.56) | KMT2AMEN1RECQLRAB9APABPC1 | |
| Hydrochloric Acid SCHEMBL10531148 | 0.84 | POLB (0.63) | KMT2AMEN1RECQLPABPC1ATM | |
| Bromide SCHEMBL10529434 | 0.84 | POLB (0.52) | KMT2AMEN1RECQLRAB9APABPC1 | |
| SCHEMBL10526841 | 0.84 | POLB (0.49) | KMT2AMEN1RECQLRAB9APABPC1 | |
| SCHEMBL10529179 | 0.84 | KMT2A (0.47) | KMT2AMEN1RECQLRAB9APABPC1 | |
| Bromide SCHEMBL3845991 | 0.83 | SMN1; SMN2 (0.52) | KMT2AMEN1RECQLRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9622469-B2 | Crosslink breakers for preservation of biological substances | SPIEGEL DAVID (US) | 2017-04-18 | — | — | US | disclosed |
| US-9622469-B2 | Crosslink breakers for preservation of biological substances | SPIEGEL DAVID (US) | 2017-04-18 | — | — | US | disclosed |
| US-20150099260-A1 | Crosslink Breakers for Preservation of Biological Substances | SPIEGEL DAVID (US) | 2015-04-09 | — | — | US | disclosed |
| US-20150099260-A1 | Crosslink Breakers for Preservation of Biological Substances | SPIEGEL DAVID (US) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099260-A1 | Crosslink Breakers for Preservation of Biological Substances | AGER, LMNA, SSB | KMT2A 3680/4885MEN1 2274/4885RECQL 2411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.