Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OGT | O15294 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624950 | 0.93 | KCNH2 (0.42) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16624945 | 0.89 | FLT3 (0.49) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16624985 | 0.89 | KCNH2 (0.56) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16624874 | 0.87 | KCNH2 (0.43) | KCNH2PTGS1SLC6A2SLC6A4CA1 | |
| SCHEMBL18031081 | 0.85 | KCNH2 (0.63) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16618280 | 0.78 | KCNH2 (0.63) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16618251 | 0.77 | KCNH2 (0.62) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16624949 | 0.77 | KCNH2 (0.63) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL18011988 | 0.76 | KCNH2 (0.62) | KCNH2PTGS2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16618234 | 0.76 | KCNH2 (0.60) | KCNH2PTGS1SLC6A2SLC6A4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049693-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | WO | disclosed |