Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624873 | 0.93 | KCNH2 (0.42) | KCNH2FLT3PTGS2PTGS1CA1 | |
| SCHEMBL16624985 | 0.90 | KCNH2 (0.56) | KCNH2FLT3PTGS2PTGS1CA1 | |
| SCHEMBL16624945 | 0.85 | FLT3 (0.49) | KCNH2FLT3PTGS2PTGS1SLC6A2 | |
| SCHEMBL16618280 | 0.85 | KCNH2 (0.63) | KCNH2FLT3PTGS2PTGS1CA1 | |
| SCHEMBL16624874 | 0.84 | KCNH2 (0.43) | KCNH2PTGS1CA1CA2CA12 | |
| SCHEMBL16618251 | 0.79 | KCNH2 (0.62) | KCNH2PTGS2PTGS1CA1CA2 | |
| SCHEMBL16624949 | 0.78 | KCNH2 (0.63) | KCNH2FLT3PTGS2PTGS1CA1 | |
| SCHEMBL18031081 | 0.78 | KCNH2 (0.63) | KCNH2PTGS2PTGS1CA1CA2 | |
| SCHEMBL18011988 | 0.78 | KCNH2 (0.62) | KCNH2PTGS2PTGS1CA1CA2 | |
| SCHEMBL16618709 | 0.77 | KCNH2 (0.59) | KCNH2PTGS2PTGS1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049693-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | WO | disclosed |