Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.49 |
| ▸ | MIF | P14174 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624873 | 0.89 | KCNH2 (0.42) | FLT3KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16618228 | 0.85 | KCNH2 (0.61) | FLT3MIFKCNH2GRM5GSK3B | |
| SCHEMBL16624950 | 0.85 | KCNH2 (0.42) | FLT3KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16624985 | 0.82 | KCNH2 (0.56) | FLT3KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16624874 | 0.81 | KCNH2 (0.43) | KCNH2PTGS1SLC6A2SLC6A4RXRA | |
| SCHEMBL18031081 | 0.75 | KCNH2 (0.63) | KCNH2PTGS1SLC6A2SLC6A4PTGS2 | |
| SCHEMBL16618217 | 0.72 | KCNH2 (0.61) | MIFKCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16618280 | 0.71 | KCNH2 (0.63) | FLT3KCNH2PTGS1SLC6A2SLC6A4 | |
| SCHEMBL16618251 | 0.71 | KCNH2 (0.62) | KCNH2PTGS1SLC6A2SLC6A4PTGS2 | |
| SCHEMBL16618223 | 0.71 | KCNH2 (0.63) | KCNH2PTGS1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049693-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | WO | disclosed |