Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19704648 | 1.00 | KCNH2 (0.65) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL19704647 | 0.92 | KCNH2 (0.66) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL16624931 | 0.92 | KCNH2 (0.66) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL19704650 | 0.92 | KCNH2 (0.66) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL16624991 | 0.92 | KCNH2 (0.66) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL19704646 | 0.90 | KCNH2 (0.68) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL19704666 | 0.90 | KCNH2 (0.82) | KCNH2PTGS1SLC6A2SLC6A4LMNA | |
| SCHEMBL18031090 | 0.90 | KCNH2 (0.82) | KCNH2PTGS1SLC6A2SLC6A4LMNA | |
| SCHEMBL18031091 | 0.90 | KCNH2 (0.68) | KCNH2PTGS1SLC6A2SLC6A4GAA | |
| SCHEMBL19704663 | 0.86 | KCNH2 (0.67) | KCNH2PTGS1SLC6A2SLC6A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845330-B2 | 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-19 | — | — | US | claimed |
| US-9845330-B2 | 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-19 | — | — | US | disclosed |
| US-9845330-B2 | 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-19 | — | — | US | disclosed |
| US-9845330-B2 | 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-19 | — | — | US | disclosed |
| US-20160244462-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-25 | — | — | US | disclosed |
| US-20160244462-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-25 | — | — | US | disclosed |
| WO-2015049693-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244462-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | XDH, DHFR, G6PD | KCNH2 3211/4885PTGS1 1195/4885SLC6A2 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.