Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604729 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL12041944 | 0.80 | KMT2A (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL29501425 | 0.80 | KMT2A (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL7920616 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL21154640 | 0.78 | KCNH2 (0.43) | ALDH1A1KCNH2HRH3KMT2A | |
| SCHEMBL25604320 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL3711581 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL30675593 | 0.77 | KCNH2 (0.43) | KCNH2HRH3 | |
| SCHEMBL20679583 | 0.77 | KCNH2 (0.43) | KCNH2HRH3 | |
| SCHEMBL29924638 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078971-A1 | NOVEL COMPOUNDS | AC IMMUNE SA (CH) | 2022-04-21 | — | — | WO | disclosed |
| US-20210252175-A1 | NOVEL COMPOUNDS FOR DIAGNOSIS | AC IMMUNE SA (CH) | 2021-08-19 | — | — | US | disclosed |
| US-20150099883-A1 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210252175-A1 | NOVEL COMPOUNDS FOR DIAGNOSIS | SNCA, PARK7, NLN | SMN1; SMN2 97/4885NPC1 1604/4885RAB9A 1610/4885 |
| US-20150099883-A1 | ARYLOXYUREA COMPOUND AND PEST CONTROL AGENT | L3MBTL4, DDT, CHRM1 | SMN1; SMN2 1634/4885NPC1 3786/4885RAB9A 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.