Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624968 | 0.93 | KCNH2 (0.62) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL16625037 | 0.92 | KCNH2 (0.79) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL16625038 | 0.91 | KCNH2 (0.64) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL18031085 | 0.91 | KCNH2 (0.64) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL16624882 | 0.89 | KCNH2 (0.63) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL16625051 | 0.89 | KCNH2 (0.59) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL18031084 | 0.88 | KCNH2 (0.60) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL19518594 | 0.87 | KCNH2 (0.59) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL19518593 | 0.87 | KCNH2 (0.59) | KCNH2PTGS1SLC6A2SLC6A4CA12 | |
| SCHEMBL5542362 | 0.87 | KCNH2 (0.73) | KCNH2PTGS1SLC6A2SLC6A4CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052503-B1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-B]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |
| US-9845330-B2 | 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-19 | — | — | US | disclosed |
| US-9845330-B2 | 6-nitro-2,3-dihydroimidazo[2,1-b]oxazoles and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-19 | — | — | US | disclosed |
| US-20160244462-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-25 | — | — | US | disclosed |
| US-20160244462-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-25 | — | — | US | disclosed |
| WO-2015049693-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244462-A1 | 6-NITRO-2,3-DIHYDROIMIDAZO[2,1-b]OXAZOLES AND A PROCESS FOR THE PREPARATION THEREOF | XDH, DHFR, G6PD | KCNH2 3211/4885PTGS1 1195/4885SLC6A2 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.