Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627248 | 0.86 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10641101 | 0.76 | ALOX5 (0.53) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10643744 | 0.75 | ALOX5 (0.53) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| Diethylamine SCHEMBL10358779 | 0.73 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10358337 | 0.73 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10643877 | 0.73 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10644925 | 0.73 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10643456 | 0.73 | ALOX5 (0.48) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL10358389 | 0.71 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10641141 | 0.71 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453844-B2 | Detection of protein S-sulfhydration via a tag-switch technique | WASHINGTON STATE UNIVERSITY (US) | 2016-09-27 | — | — | US | disclosed |
| US-20150099305-A1 | DETECTION OF PROTEIN S-SULFHYDRATION VIA A TAG-SWITCH TECHNIQUE | NATIONAL SCIENCE FOUNDATION | 2015-04-09 | — | — | US | disclosed |