Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756873 | 0.93 | GNAO1 (0.47) | GNAI3GNAO1GNAI1NOS3NOS1 | |
| SCHEMBL29532370 | 0.87 | GNAO1 (0.55) | GNAI3GNAO1GNAI1 | |
| SCHEMBL16625964 | 0.86 | BCHE (0.44) | BCHE | |
| SCHEMBL29531997 | 0.86 | GNAO1 (0.58) | GNAI3GNAO1GNAI1 | |
| SCHEMBL28863184 | 0.83 | GNAO1 (0.40) | GNAI3GNAO1GNAI1NOS3NOS1 | |
| SCHEMBL30379435 | 0.82 | GNAI3 (0.41) | GNAI3GNAO1GNAI1 | |
| SCHEMBL9869321 | 0.82 | GNAI3 (0.41) | GNAI3GNAO1GNAI1 | |
| SCHEMBL24789538 | 0.82 | HRH3 (0.39) | HRH3POLBNOS3NOS1NOS2 | |
| SCHEMBL10511195 | 0.81 | BCHE (0.40) | MAPTBCHE | |
| SCHEMBL13167818 | 0.81 | HRH3 (0.45) | GNAI3GNAO1GNAI1HRH3NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050471-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |