Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661173 | 0.93 | L3MBTL1 (0.41) | POLBHRH3ALDH1A1THRBL3MBTL1 | |
| SCHEMBL1180845 | 0.91 | POLB (0.46) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| SCHEMBL8114400 | 0.91 | POLB (0.46) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| Bromide SCHEMBL3742304 | 0.89 | POLB (0.45) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL3727010 | 0.89 | POLB (0.45) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| Iodide SCHEMBL1514951 | 0.89 | POLB (0.45) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| SCHEMBL11848972 | 0.86 | ALOX5 (0.47) | HRH3ALOX5 | |
| Dimethylamine SCHEMBL6946290 | 0.85 | POLB (0.42) | POLBALDH1A1THRBL3MBTL1NPC1 | |
| SCHEMBL2859361 | 0.83 | ALDH1A1 (0.41) | POLBALDH1A1THRBL3MBTL1BRD4 | |
| SCHEMBL6954713 | 0.83 | ALOX5 (0.43) | HRH3ALDH1A1THRBL3MBTL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050471-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-04-09 | — | — | WO | disclosed |