Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626433 | 0.90 | EGFR (0.33) | EGFR | |
| SCHEMBL16626693 | 0.89 | TBXAS1 (0.31) | MEN1MAPTPABPC1KMT2AEGFR | |
| SCHEMBL19984214 | 0.89 | MEN1 (0.32) | MEN1MAPTKMT2AEGFRNAMPT | |
| SCHEMBL16626424 | 0.88 | MAPK14 (0.36) | MAPTNAMPT | |
| SCHEMBL16626468 | 0.86 | METAP2 (0.30) | METAP2 | |
| SCHEMBL19983986 | 0.86 | ALDH1A1 (0.31) | EGFR | |
| SCHEMBL19984086 | 0.85 | EGFR (0.34) | EGFRHTR2C | |
| SCHEMBL16626477 | 0.85 | — | — | |
| SCHEMBL16626730 | 0.85 | EGFR (0.38) | MEN1MAPTKMT2AEGFRNAMPT | |
| SCHEMBL16626459 | 0.85 | GAA (0.39) | MEN1MAPTKMT2ACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |