Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626457 | 0.86 | PARP14 (0.33) | GRM4 | |
| SCHEMBL19984214 | 0.85 | MEN1 (0.32) | EGFRNAMPTMAPTALDH1A1LMNA | |
| SCHEMBL19984136 | 0.85 | MEN1 (0.39) | EGFRNAMPTMAPTMEN1KMT2A | |
| SCHEMBL16626468 | 0.84 | METAP2 (0.30) | — | |
| SCHEMBL16626715 | 0.84 | GRM4 (0.33) | EGFRGRM4 | |
| SCHEMBL16626464 | 0.83 | NAMPT (0.35) | NAMPTJAK2JAK3PTK2GRM4 | |
| SCHEMBL16626476 | 0.82 | — | — | |
| SCHEMBL16626459 | 0.82 | GAA (0.39) | NAMPTNPC1MAPTALDH1A1LMNA | |
| SCHEMBL16626672 | 0.82 | ALDH1A1 (0.35) | NAMPTNPC1MAPTHTTALDH1A1 | |
| SCHEMBL16626433 | 0.82 | EGFR (0.33) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |