Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB3 | P54753 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4917986 | 0.79 | HTR2A (0.44) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL2809874 | 0.77 | ALDH1A1 (0.49) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL4917094 | 0.76 | HTR2A (0.45) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL35264 | 0.76 | PTGS1 (0.45) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL12686677 | 0.76 | SPR (0.45) | ALDH1A1CYP2C9MIFTSHRPDE4B | |
| SCHEMBL16223183 | 0.75 | MIF (0.44) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL4183274 | 0.75 | EGFR (0.36) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL5133264 | 0.74 | APOBEC3A (0.45) | ALDH1A1MEN1KMT2AELANEHPGD | |
| SCHEMBL1665454 | 0.73 | EGFR (0.40) | EPHB3ALDH1A1CYP2C9MIFTSHR | |
| SCHEMBL35212140 | 0.72 | MIF (0.41) | EPHB3ALDH1A1CYP2C9MIFTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |