Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 5/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428622 | 0.87 | IRAK4 (0.42) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1KCNQ3 | |
| SCHEMBL3712511 | 0.76 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1HPGD | |
| SCHEMBL30627413 | 0.76 | ELANE (0.42) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1KCNQ3 | |
| SCHEMBL1662676 | 0.74 | EPHB3 (0.39) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL27110045 | 0.73 | KCNQ3 (0.51) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1KCNQ3 | |
| SCHEMBL27110046 | 0.72 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1KCNQ3 | |
| SCHEMBL4867147 | 0.69 | KCNQ3 (0.52) | KCNQ3KCNQ2 | |
| SCHEMBL17460386 | 0.69 | IRAK4 (0.45) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1KCNQ3 | |
| Trifluoroacetic Acid SCHEMBL30194359 | 0.69 | PIK3CG (0.42) | PIK3CG | |
| SCHEMBL17460367 | 0.69 | ALDH1A1 (0.46) | APOBEC3AALDH1A1L3MBTL1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-A4 | PYRAZOLOPYRIMIDINES | ICAGEN INC (US) | 2008-01-02 | — | — | EP | disclosed |
| EP-1506196-A2 | PYRAZOLOPYRIMIDINES | Icagen, Inc. (US) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003037900-A2 | PYRAZOLOPYRIMIDINES | ICAGEN, INC. (US) | 2003-05-08 | — | — | WO | disclosed |