Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 13/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626586 | 0.82 | EPHX2 (0.38) | METAP2USP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16626086 | 0.81 | GRIN2B (0.38) | METAP2 | |
| SCHEMBL16626590 | 0.80 | L3MBTL1 (0.33) | USP2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19984151 | 0.79 | — | — | |
| SCHEMBL19984008 | 0.78 | — | — | |
| SCHEMBL17971568 | 0.78 | METAP2 (0.41) | METAP2SCN9ANR1D1 | |
| SCHEMBL16626466 | 0.78 | METAP2 (0.31) | METAP2 | |
| Hydrochloric Acid SCHEMBL16618831 | 0.78 | METAP2 (0.41) | METAP2SCN9ANR1D1 | |
| SCHEMBL16626468 | 0.77 | METAP2 (0.30) | METAP2 | |
| SCHEMBL16626457 | 0.77 | PARP14 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |