Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626590 | 0.88 | L3MBTL1 (0.33) | EPHX2PRMT6NR1D1CYP2C19CYP2D6 | |
| SCHEMBL16626086 | 0.84 | GRIN2B (0.38) | EPHX2PRMT6METAP2 | |
| SCHEMBL16626766 | 0.82 | METAP2 (0.40) | NR1D1CYP2C19CYP2D6CYP2C9METAP2 | |
| SCHEMBL19983774 | 0.82 | BACE1 (0.34) | NR1D1HDAC8 | |
| SCHEMBL16626750 | 0.81 | RAB9A (0.36) | EPHX2PRMT6KDM4EHPGDLMNA | |
| SCHEMBL16626643 | 0.80 | BACE1 (0.35) | NR1D1 | |
| SCHEMBL16626676 | 0.80 | P2RX7 (0.38) | EPHX2PRMT6CHEK1HTR2C | |
| SCHEMBL19984214 | 0.79 | MEN1 (0.32) | LMNAMAPK1HTR2CMEN1ALDH1A1 | |
| SCHEMBL19984136 | 0.79 | MEN1 (0.39) | METAP2HTR2CMEN1KMT2A | |
| SCHEMBL16626433 | 0.78 | EGFR (0.33) | EPHX2PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050412-A1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-04-09 | — | — | WO | disclosed |