SCHEMBL16626971

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17783289	0.86	CYP2A6 (0.39)	KIF11KDM4EMEN1KMT2AALDH1A1
	SCHEMBL16626973	0.79	MAOA (0.37)	KIF11ESR1ESR2ERN1KDM4E
	SCHEMBL17083204	0.77	ESR1 (0.64)	KIF11ESR1ESR2MEN1KMT2A
	SCHEMBL18137076	0.77	ESR1 (0.42)	ESR1ESR2ERN1KDM4EMEN1
	SCHEMBL16037967	0.76	KIF11 (0.59)	KIF11DRD1ERN1PTGS1ALDH1A1
	SCHEMBL16626972	0.73	KIF11 (0.49)	KIF11ESR1ESR2ERN1PTGS1
	SCHEMBL17831342	0.72	KIF11 (0.56)	KIF11ESR1ESR2DRD1ERN1
	SCHEMBL3457040	0.72	KIF11 (0.65)	KIF11DRD1ERN1PTGS1TRIM24
	SCHEMBL16055912	0.72	KIF11 (0.46)	KIF11ESR1ESR2DRD1KDM4E
	SCHEMBL13419515	0.71	HPRT1 (0.38)	KIF11ESR1ESR2ERN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.