Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17083204 | 0.81 | ESR1 (0.64) | KIF11ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL14525987 | 0.81 | MCL1 (0.40) | ESR1ESR2CYP11B1CYP17A1TAAR1 | |
| SCHEMBL15088587 | 0.80 | CHKA (0.36) | KIF11ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL18137076 | 0.77 | ESR1 (0.42) | ERN1ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL15088582 | 0.77 | HSD17B1 (0.37) | KIF11ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL15725297 | 0.76 | KIF11 (0.59) | KIF11ERN1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL14152972 | 0.76 | KIF11 (0.59) | KIF11ERN1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL20209578 | 0.76 | TAAR1 (0.43) | ESR1ESR2HSD17B1HSD17B2CHEK1 | |
| SCHEMBL15088584 | 0.75 | ESR1 (0.35) | KIF11ESR1ESR2TAAR1 | |
| SCHEMBL28587584 | 0.75 | NOS3 (0.33) | ESR1ESR2CYP11B1CYP17A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573923-B2 | Liquid crystal compound having 2, 6-difluorophenylether structure, and liquid crystal composition containing the same | DIC CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9573923-B2 | Liquid crystal compound having 2, 6-difluorophenylether structure, and liquid crystal composition containing the same | DIC CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9573923-B2 | Liquid crystal compound having 2, 6-difluorophenylether structure, and liquid crystal composition containing the same | DIC CORPORATION (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DIC CORPORATION (JP) | 2016-06-09 | — | — | US | disclosed |
| WO-2015049940-A1 | LIQUID CRYSTALLINE COMPOUND HAVING 2,6-DIFLUOROPHENYL ETHER STRUCTURE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | DIC株式会社 | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159765-A1 | LIQUID CRYSTAL COMPOUND HAVING 2, 6-DIFLUOROPHENYLETHER STRUCTURE, AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | FGFR2, FGFR1, FGF2 | KIF11 184/4885ERN1 1652/4885ESR1 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.