Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662862 | 0.84 | ALDH1A1 (0.46) | MAPTKDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL3649415 | 0.81 | MAPT (0.47) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1663480 | 0.81 | MAPT (0.43) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1663471 | 0.81 | MAPT (0.45) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1665603 | 0.81 | MAPT (0.45) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1663210 | 0.80 | MAPT (0.44) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1662566 | 0.79 | MAPT (0.41) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1662624 | 0.78 | MAPT (0.43) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1663272 | 0.76 | MAPT (0.41) | MAPTTTRUSP2KDM4EHSD17B10 | |
| SCHEMBL1719409 | 0.73 | MAPT (0.69) | MAPTUSP2KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |