Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663326 | 0.86 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1HSD17B10CASP1 | |
| SCHEMBL1663471 | 0.82 | MAPT (0.45) | MAPTTTRUSP2PKMKDM4E | |
| SCHEMBL1662704 | 0.81 | MAPT (0.44) | MAPTTTRUSP2KDM4EALDH1A1 | |
| SCHEMBL1663210 | 0.81 | MAPT (0.44) | MAPTTTRUSP2PKMKDM4E | |
| SCHEMBL1663480 | 0.79 | MAPT (0.43) | MAPTTTRUSP2PKMKDM4E | |
| SCHEMBL3649415 | 0.79 | MAPT (0.47) | MAPTTTRUSP2KDM4EALDH1A1 | |
| SCHEMBL1662566 | 0.77 | MAPT (0.41) | MAPTTTRUSP2PKMKDM4E | |
| SCHEMBL1663272 | 0.77 | MAPT (0.41) | MAPTTTRUSP2PKMKDM4E | |
| SCHEMBL1664938 | 0.77 | ALDH1A1 (0.39) | MAPTKDM4EALDH1A1HSD17B10CASP1 | |
| SCHEMBL12794883 | 0.77 | HSP90AA1 (0.40) | USP2ALDH1A1CASP1GAACASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |