Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663210 | 0.88 | MAPT (0.44) | MAPTKDM4EALDH1A1PKMUSP2 | |
| SCHEMBL1663480 | 0.84 | MAPT (0.43) | MAPTKDM4EALDH1A1PKMUSP2 | |
| SCHEMBL12794882 | 0.79 | HSP90AA1 (0.37) | ALDH1A1USP2CASP1GAACASP7 | |
| SCHEMBL1665603 | 0.77 | MAPT (0.45) | MAPTKDM4EALDH1A1PKMUSP2 | |
| SCHEMBL1663471 | 0.77 | MAPT (0.45) | MAPTKDM4EALDH1A1PKMUSP2 | |
| SCHEMBL1662704 | 0.76 | MAPT (0.44) | MAPTKDM4EALDH1A1USP2TTR | |
| SCHEMBL1663187 | 0.74 | MAPT (0.40) | MAPTKDM4EALDH1A1PKMHSD17B10 | |
| SCHEMBL3649415 | 0.74 | MAPT (0.47) | MAPTKDM4EALDH1A1USP2TTR | |
| SCHEMBL1662624 | 0.74 | MAPT (0.43) | MAPTKDM4EALDH1A1PKMUSP2 | |
| SCHEMBL1662801 | 0.73 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |