Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954297 | 0.92 | FYN (0.43) | FYNMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16624805 | 0.91 | ACSS2 (0.42) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20101406 | 0.86 | FFAR1 (0.41) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16624624 | 0.85 | CYP4F2 (0.42) | MAPTSMN1; SMN2CYP11B1CYP11B2FFAR1 | |
| SCHEMBL16624803 | 0.83 | MRGPRX4 (0.47) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16618237 | 0.82 | MAOB (0.47) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17954293 | 0.82 | CYP11B1 (0.45) | FYNMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL17954315 | 0.82 | CASP3 (0.46) | FYNMAPTSMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL16624847 | 0.81 | CASP3 (0.50) | MAPTSMN1; SMN2CYP11B1CYP11B2CASP3 | |
| SCHEMBL16624801 | 0.81 | FFAR1 (0.47) | MAPTKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051044-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |