Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954315 | 0.90 | CASP3 (0.46) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16624805 | 0.84 | ACSS2 (0.42) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL19021001 | 0.84 | LTA4H (0.46) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL17954293 | 0.84 | CYP11B1 (0.45) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16628094 | 0.84 | CYP11B1 (0.45) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16624624 | 0.83 | CYP4F2 (0.42) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16631062 | 0.83 | CYP11B1 (0.47) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16624848 | 0.82 | DGAT1 (0.41) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16627148 | 0.81 | FYN (0.39) | CASP3SENP8SENP7SENP6CYP11B1 | |
| SCHEMBL16627145 | 0.81 | LTA4H (0.41) | RAB9ANPC1SMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050871-A2 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |
| WO-2015051366-A2 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |