Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16625019 | 0.96 | TACR3 (0.43) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL16625017 | 0.88 | FBP1 (0.51) | ALDH1A1CYP2C19HSD17B10FBP1POLB | |
| SCHEMBL16627194 | 0.84 | L3MBTL1 (0.50) | ALDH1A1HSD17B10FBP1POLBATM | |
| SCHEMBL16625021 | 0.83 | FBP1 (0.49) | ALDH1A1HSD17B10FBP1POLBHPGD | |
| SCHEMBL16625024 | 0.81 | FBP1 (0.54) | ALDH1A1HSD17B10FBP1POLBHPGD | |
| SCHEMBL16625026 | 0.80 | CYP26A1 (0.48) | ALDH1A1THRBHSD17B10FBP1POLB | |
| SCHEMBL3734223 | 0.76 | ALDH1A1 (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL27488362 | 0.76 | ALDH1A1 (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL1884230 | 0.74 | ATM (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL1879654 | 0.74 | ATM (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453844-B2 | Detection of protein S-sulfhydration via a tag-switch technique | WASHINGTON STATE UNIVERSITY (US) | 2016-09-27 | — | — | US | disclosed |
| US-20150099305-A1 | DETECTION OF PROTEIN S-SULFHYDRATION VIA A TAG-SWITCH TECHNIQUE | NATIONAL SCIENCE FOUNDATION | 2015-04-09 | — | — | US | disclosed |