Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663132 | 0.68 | NFKB1 (0.39) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL6711098 | 0.67 | NFKB1 (0.43) | NFKB1NFKB2RELAMAPK1MT-CO2 | |
| SCHEMBL6343913 | 0.67 | NFKB1 (0.43) | NFKB1NFKB2RELAMAPK1MT-CO2 | |
| SCHEMBL6343911 | 0.67 | NFKB1 (0.43) | NFKB1NFKB2RELAMAPK1MT-CO2 | |
| SCHEMBL15934978 | 0.65 | NFKB1 (0.36) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL17770853 | 0.65 | CCR2 (0.44) | NFKB1NFKB2RELA | |
| SCHEMBL17991583 | 0.65 | NFKB1 (0.49) | NFKB1NFKB2RELAGAA | |
| SCHEMBL24969074 | 0.65 | NFKB1 (0.41) | NFKB1NFKB2RELAMAPK1MT-CO2 | |
| SCHEMBL31236401 | 0.63 | HSD11B1 (0.41) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL24062321 | 0.63 | ASGR1 (0.37) | NFKB1NFKB2RELAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |