Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.52 |
| ▸ | CBFB | Q13951 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627418 | 0.85 | RAB9A (0.57) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL16627414 | 0.85 | RAB9A (0.79) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL16627416 | 0.83 | ALDH1A1 (0.55) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL13748719 | 0.83 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL16627424 | 0.81 | ALDH1A1 (0.53) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL16638724 | 0.81 | ALDH1A1 (0.50) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL16627411 | 0.79 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10938235 | 0.79 | AKR1C3 (0.56) | ALDH1A1MAPTGAALMNAKDM4E | |
| SCHEMBL16627429 | 0.79 | MAPT (0.58) | ALDH1A1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL16627415 | 0.78 | GAA (0.56) | ALDH1A1RAB9ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | HCCS, WEE2, WEE1 | ALDH1A1 1497/4885RAB9A 1415/4885SMN1; SMN2 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.