Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 4/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797287 | 0.86 | MEN1 (0.53) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL16627422 | 0.83 | ALDH1A1 (0.58) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL16638721 | 0.82 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL16627414 | 0.82 | RAB9A (0.79) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL16627418 | 0.82 | RAB9A (0.57) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL10937347 | 0.80 | GAA (0.57) | ALDH1A1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL16616459 | 0.80 | MEN1 (0.80) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL16627412 | 0.80 | ADRA2A (0.44) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL13748719 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL16627430 | 0.80 | MEN1 (0.81) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006451-B1 | 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-14 | — | — | US | disclosed |
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099888-A1 | 2-Anilinonicotinyl Based Chalcones Useful As Potential Anticancer Agents and Process for Preparation Thereof | HCCS, WEE2, WEE1 | ALDH1A1 1497/4885RAB9A 1415/4885SMN1; SMN2 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.