Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627490 | 0.86 | NTSR1 (0.44) | HTR2AHTR2CNTSR1SLC6A2SLC6A4 | |
| SCHEMBL16627486 | 0.86 | NTSR1 (0.44) | HTR2AHTR2CNTSR1SLC6A2SLC6A4 | |
| SCHEMBL3681424 | 0.85 | GAA (0.40) | LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3688516 | 0.84 | TSHR (0.37) | FPR2TSHR | |
| SCHEMBL13509571 | 0.83 | CA12 (0.41) | FPR2HTTTSHR | |
| SCHEMBL16627458 | 0.81 | NTSR1 (0.50) | FPR2HTR2AHTR2CNTSR1SLC6A2 | |
| SCHEMBL16619844 | 0.81 | NTSR1 (0.50) | FPR2HTR2AHTR2CNTSR1SLC6A2 | |
| SCHEMBL22798848 | 0.81 | NTSR1 (0.50) | FPR2HTR2AHTR2CNTSR1SLC6A2 | |
| SCHEMBL6706690 | 0.80 | PTPN1 (0.44) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL2012022 | 0.80 | HTR2A (0.49) | HTR2AHTR2CNTSR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049668-A1 | NOVEL COMPOUND AS A DIACYLGLYCEROL ACYLTRANSFERASE INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |