Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP2 | P12104 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627490 | 1.00 | NTSR1 (0.44) | NTSR1HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL16627489 | 0.86 | FPR2 (0.45) | NTSR1HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL2000984 | 0.84 | NR3C2 (0.39) | SLC6A2SLC6A4NR3C2KMT2ATP53 | |
| SCHEMBL2000119 | 0.84 | NR3C2 (0.39) | SLC6A2SLC6A4NR3C2KMT2ATP53 | |
| SCHEMBL22798848 | 0.84 | NTSR1 (0.50) | NTSR1HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL16619844 | 0.84 | NTSR1 (0.50) | NTSR1HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL16627458 | 0.84 | NTSR1 (0.50) | NTSR1HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL2012022 | 0.82 | HTR2A (0.49) | NTSR1HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL2182449 | 0.79 | NR3C2 (0.53) | SLC6A2SLC6A4NR3C2KMT2A | |
| SCHEMBL1995408 | 0.77 | ITGB3 (0.41) | SLC6A2SLC6A4MCL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049668-A1 | NOVEL COMPOUND AS A DIACYLGLYCEROL ACYLTRANSFERASE INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |