Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798848 | 1.00 | NTSR1 (0.50) | NTSR1HTR2AHTR2CMCL1FABP4 | |
| SCHEMBL16627458 | 1.00 | NTSR1 (0.50) | NTSR1HTR2AHTR2CMCL1FABP4 | |
| SCHEMBL2012022 | 0.86 | HTR2A (0.49) | NTSR1HTR2AHTR2CMCL1FABP4 | |
| SCHEMBL16627490 | 0.84 | NTSR1 (0.44) | NTSR1HTR2AHTR2CMCL1FABP4 | |
| SCHEMBL16627486 | 0.84 | NTSR1 (0.44) | NTSR1HTR2AHTR2CMCL1FABP4 | |
| SCHEMBL6258605 | 0.83 | HTR2A (0.45) | HTR2AHTR2CFABP4SLC6A2SLC6A4 | |
| SCHEMBL2002647 | 0.83 | PTGS2 (0.38) | NTSR1PTGS2 | |
| SCHEMBL16627489 | 0.81 | FPR2 (0.45) | NTSR1HTR2AHTR2CMCL1SLC6A2 | |
| SCHEMBL22798770 | 0.81 | SLC6A2 (0.48) | HTR2AHTR2CSLC6A2SLC6A4PTGS2 | |
| SCHEMBL22798768 | 0.81 | SLC6A2 (0.48) | HTR2AHTR2CSLC6A2SLC6A4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753560-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD Pharma A/S (DK) | 2020-12-23 | — | — | EP | claimed |
| EP-3753560-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD Pharma A/S (DK) | 2020-12-23 | — | — | EP | disclosed |
| WO-2015049668-A1 | NOVEL COMPOUND AS A DIACYLGLYCEROL ACYLTRANSFERASE INHIBITOR | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |