Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955356 | 0.93 | HSD17B2 (0.70) | MEN1KMT2AHSD17B2KDM4EPOLB | |
| SCHEMBL31438953 | 0.90 | TDP1 (0.57) | MEN1KMT2AHSD17B2KDM4EPOLB | |
| SCHEMBL22283475 | 0.90 | TDP1 (0.57) | MEN1KMT2AHSD17B2KDM4EPOLB | |
| SCHEMBL4734462 | 0.87 | HSD17B2 (0.55) | HSD17B2KDM4EPOLBHDAC6ALDH1A1 | |
| SCHEMBL4955367 | 0.85 | HSD17B2 (0.60) | MEN1KMT2AHSD17B2KDM4EPOLB | |
| SCHEMBL1356478 | 0.85 | HSD17B2 (0.72) | MEN1KMT2AHSD17B2KDM4EPOLB | |
| SCHEMBL1354883 | 0.84 | HSD17B2 (0.67) | MEN1KMT2AHSD17B2KDM4EPOLB | |
| SCHEMBL1660661 | 0.83 | CA12 (0.57) | MEN1KMT2AALDH1A1GAATSHR | |
| SCHEMBL31694578 | 0.83 | TSHR (0.63) | HSD17B2ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL20440722 | 0.83 | TSHR (0.63) | HSD17B2ALDH1A1GAATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340719-B1 | Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners | SYMRISE AG (DE) | 2014-02-19 | — | — | EP | claimed |
| EP-2340719-A1 | Aroma composition comprising o-coumaric acid to reduce or suppress undesirable taste impressions of sweeteners | Symrise AG (DE) | 2011-07-06 | — | — | EP | claimed |
| EP-2220945-A1 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | Symrise GmbH & Co. KG (DE) | 2010-08-25 | — | — | EP | claimed |
| US-20100151055-A1 | Aroma Composition to Reduce or Suppress Undesirable Bitter and Astringent Taste Impressions of Sweeteners | SYMRISE GMBH & CO. KG (DE) | 2010-06-17 | — | — | US | claimed |
| US-20220157484-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-05-19 | — | — | US | disclosed |
| CN-109310130-B | Cooling substance mixture | 西姆莱斯股份公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-104886258-B | Protein material used as cheese substitute | DMK德意志牛奶股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| US-9848624-B2 | Use of rubusoside for reducing or suppressing certain unpleasant taste impressions | SYMRISE AG (DE) | 2017-12-26 | — | — | US | disclosed |
| US-9642381-B2 | Orally consumable formulations comprising certain sweet-tasting triterpenes and triterpene glycosides | SYMRISE AG (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9545119-B2 | Specific vanillyl lignans and use thereof as taste improvers | SYMRISE AG (DE) | 2017-01-17 | — | — | US | disclosed |
| US-9198451-B2 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | SYMRISE AG (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9131716-B2 | Use of neoflavonoids for flavor modification | SYMRISE AG (DE) | 2015-09-15 | — | — | US | disclosed |
| EP-2220945-A1 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | Symrise GmbH & Co. KG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100151055-A1 | Aroma Composition to Reduce or Suppress Undesirable Bitter and Astringent Taste Impressions of Sweeteners | SYMRISE GMBH & CO. KG (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20100080880-A1 | GERANYLAMINE DERIVATES OF OXALIC ACID | SYMRISE GMBH & CO. KG (DE) | 2010-04-01 | — | — | US | disclosed |
| CN-101611857-A | New menthyl derivatives as flavor substance | SYMRISE GMBH & CO KG DE | 2009-12-30 | — | — | CN | disclosed |
| CN-101528060-A | Substituted bicyclo[4.1.0]heptane-7-carboxylic acid amides and derivatives thereof as food flavor substances | SYMRISE GMBH & CO KG (DE) | 2009-09-09 | — | — | CN | disclosed |
| CN-101422229-A | Romatic neomenthylamides as flavouring agents | SYMRISE GMBH & CO KG (DE) | 2009-05-06 | — | — | CN | disclosed |
| US-20080292763-A1 | Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance | SYMRISE GMBH & CO. KG (DE) | 2008-11-27 | — | — | US | disclosed |
| CN-101301064-A | Substituted cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance | SYMRISE GMBH & CO (DE) | 2008-11-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100080880-A1 | GERANYLAMINE DERIVATES OF OXALIC ACID | OTC, OAT, ODC1 | MEN1 358/4885KMT2A 3471/4885HSD17B2 4479/4885 |
| US-20080292763-A1 | Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance | TAS1R1, TAS2R1, TAS1R3 | MEN1 1848/4885KMT2A 1290/4885HSD17B2 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.