Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468791 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627891 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627713 | 0.88 | CNR2 (0.59) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627831 | 0.88 | KDM4E (0.51) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627739 | 0.87 | SMYD3 (0.50) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627887 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL34468766 | 0.84 | SMYD3 (0.49) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627868 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1KMT2ASMYD3NPC1 | |
| SCHEMBL16627706 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL34468807 | 0.81 | PARP1 (0.50) | KDM4EALDH1A1KMT2ASMYD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |