Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627774 | 0.90 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16627831 | 0.84 | KDM4E (0.51) | ALDH1A1SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL34468791 | 0.83 | KDM4E (0.62) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16627891 | 0.82 | KDM4E (0.52) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16627758 | 0.82 | NPC1 (0.55) | ALDH1A1SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL16627593 | 0.82 | KDM4E (0.51) | ALDH1A1SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL16627713 | 0.82 | CNR2 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16627739 | 0.80 | SMYD3 (0.50) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16627868 | 0.80 | KDM4E (0.48) | ALDH1A1NPC1TP53KMT2AMEN1 | |
| SCHEMBL16627887 | 0.79 | KDM4E (0.48) | ALDH1A1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |