Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627739 | 0.83 | SMYD3 (0.50) | KDM4ENPC1HTTALDH1A1L3MBTL1 | |
| SCHEMBL34468791 | 0.82 | KDM4E (0.62) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL16627891 | 0.81 | KDM4E (0.52) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL16627735 | 0.81 | MEN1 (0.47) | KDM4ENPC1LMNAFAAHRAB9A | |
| SCHEMBL34468766 | 0.81 | SMYD3 (0.49) | KDM4ENPC1HTTALDH1A1LMNA | |
| SCHEMBL16627868 | 0.81 | KDM4E (0.48) | KDM4ENPC1HTTALDH1A1L3MBTL1 | |
| SCHEMBL16627831 | 0.80 | KDM4E (0.51) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL16627593 | 0.80 | KDM4E (0.51) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL16627713 | 0.80 | CNR2 (0.59) | KDM4ENPC1ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL34468807 | 0.78 | PARP1 (0.50) | KDM4ENPC1ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |