Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627734 | 0.88 | MEN1 (0.58) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL16627728 | 0.81 | KDM4E (0.56) | LMNANPC1RAB9AKDM4ETSHR | |
| SCHEMBL16627807 | 0.78 | MEN1 (0.52) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL16627809 | 0.72 | BRD4 (0.51) | KDM4ETSHR | |
| SCHEMBL16627856 | 0.69 | BRD4 (0.54) | LMNAKDM4ETSHRMAPK1 | |
| SCHEMBL7591960 | 0.69 | MMP2 (0.50) | LMNAKDM4ETSHRCNR1 | |
| SCHEMBL16627733 | 0.69 | MAPT (0.45) | MEN1KMT2AKDM4E | |
| SCHEMBL4069193 | 0.68 | KDM4E (0.75) | MEN1KMT2ALMNAPOLBKDM4E | |
| SCHEMBL30496700 | 0.68 | POLB (0.66) | MEN1KMT2ALMNAPOLBKDM4E | |
| SCHEMBL16627872 | 0.68 | CNR1 (0.52) | MEN1KMT2ALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |