Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627741 | 0.92 | AHR (0.61) | AHRKMT2AMEN1RAB9AMAOA | |
| SCHEMBL16627757 | 0.89 | AHR (0.72) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16627762 | 0.87 | AHR (0.56) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16627820 | 0.85 | AHR (1.00) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL30237030 | 0.79 | AHR (0.85) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL1397253 | 0.79 | AHR (0.85) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16627568 | 0.79 | CA12 (0.51) | POLBLMNAALDH1A1HPGDCNR1 | |
| SCHEMBL16627668 | 0.78 | AHR (0.77) | AHRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6547150 | 0.76 | MAPK1 (0.47) | KMT2ANPC1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16627821 | 0.76 | AHR (0.83) | AHRKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |