Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.72 |
| ▸ | CNR1 | P21554 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627741 | 0.91 | AHR (0.61) | AHRCNR1CNR2MAOAMAOB | |
| SCHEMBL16627748 | 0.89 | AHR (0.73) | AHRCNR1KDM4ESMN1; SMN2CNR2 | |
| SCHEMBL16627762 | 0.86 | AHR (0.56) | AHRCNR1CNR2MAOAMAOB | |
| SCHEMBL16627756 | 0.84 | AHR (1.00) | AHRCNR1MAOAMAOBTP53 | |
| SCHEMBL16627568 | 0.78 | CA12 (0.51) | CNR1KDM4ECNR2 | |
| SCHEMBL30237030 | 0.76 | AHR (0.85) | AHRMAOAMAOBMEN1KMT2A | |
| SCHEMBL1397253 | 0.76 | AHR (0.85) | AHRMAOAMAOBMEN1KMT2A | |
| SCHEMBL6547150 | 0.75 | MAPK1 (0.47) | CNR1KDM4ESMN1; SMN2CNR2KMT2A | |
| SCHEMBL16627668 | 0.75 | AHR (0.77) | AHRSMN1; SMN2MAOAMAOBTP53 | |
| SCHEMBL16627665 | 0.74 | SMN1; SMN2 (0.51) | AHRCNR1KDM4ESMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |