Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 6/20 | 0.45 |
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627741 | 0.89 | AHR (0.61) | AHRMAPTTP53MEN1KMT2A | |
| SCHEMBL16627748 | 0.87 | AHR (0.73) | AHRMAPTTP53MEN1KMT2A | |
| SCHEMBL16627757 | 0.86 | AHR (0.72) | AHRMAPTTP53MEN1KMT2A | |
| SCHEMBL16627658 | 0.81 | CNR1 (0.50) | AHRCNR1CNR2 | |
| SCHEMBL16627568 | 0.76 | CA12 (0.51) | CNR1CNR2POLBMAPK1ALDH1A1 | |
| SCHEMBL16627681 | 0.75 | NPY5R (0.45) | MAPTMEN1KMT2APOLBMAPK1 | |
| SCHEMBL30237030 | 0.74 | AHR (0.85) | AHRMEN1KMT2AMAOBPOLB | |
| SCHEMBL1397253 | 0.74 | AHR (0.85) | AHRMEN1KMT2AMAOBPOLB | |
| SCHEMBL6547150 | 0.73 | MAPK1 (0.47) | KMT2ACNR1CNR2MAPK1ALDH1A1 | |
| SCHEMBL16627765 | 0.73 | MAPK1 (0.47) | MAPTTP53CNR1CNR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |