Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627568 | 0.84 | CA12 (0.51) | MAPK1CASP1CASP7CNR1CNR2 | |
| SCHEMBL6547150 | 0.82 | MAPK1 (0.47) | MAPK1CASP1CASP7CNR1CNR2 | |
| SCHEMBL16627889 | 0.78 | L3MBTL1 (0.41) | MAPK1CNR1CNR2KDM4ELMNA | |
| SCHEMBL11824046 | 0.78 | DAO (0.62) | MAPK1CASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL16627741 | 0.77 | AHR (0.61) | CNR1CNR2ALDH1A1TP53MAPT | |
| SCHEMBL434663 | 0.77 | KDM4E (0.50) | MAPK1CASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL16627569 | 0.75 | CNR1 (0.60) | MAPK1CNR1CNR2KDM4EALDH1A1 | |
| SCHEMBL30355091 | 0.74 | BTK (0.48) | MAPK1CASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL26620879 | 0.74 | KDM4E (0.47) | MAPK1CASP1CASP7KDM4EALDH1A1 | |
| SCHEMBL28325706 | 0.74 | LMNA (0.48) | MAPK1CASP1CASP7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |