Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627775 | 0.94 | CNR1 (0.49) | RAB9ASMN1; SMN2NPC1TAAR1MAPT | |
| SCHEMBL16627771 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTCNR1CNR2ALDH1A1 | |
| SCHEMBL16627770 | 0.74 | KMT2A (0.57) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16627836 | 0.74 | NR1H2 (0.42) | NPC1MAPTCNR1CNR2MEN1 | |
| SCHEMBL16627769 | 0.74 | CNR1 (0.47) | SMN1; SMN2CNR1CNR2MEN1KMT2A | |
| SCHEMBL16627636 | 0.73 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1TAAR1MAPT | |
| SCHEMBL11053552 | 0.72 | CA1 (0.56) | RAB9ASMN1; SMN2NPC1CNR1CNR2 | |
| SCHEMBL16627679 | 0.72 | NPC1 (0.58) | RAB9ASMN1; SMN2NPC1MAPTCNR2 | |
| SCHEMBL16627744 | 0.72 | MEN1 (0.49) | RAB9ASMN1; SMN2NPC1MAPTCNR1 | |
| SCHEMBL16627657 | 0.72 | NPC1 (0.48) | RAB9ASMN1; SMN2NPC1TAAR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |