Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627769 | 0.91 | CNR1 (0.47) | SMN1; SMN2MEN1KMT2AADORA2ACNR1 | |
| SCHEMBL16627772 | 0.82 | RAB9A (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16627775 | 0.76 | CNR1 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16627882 | 0.75 | KMT2A (0.43) | SMN1; SMN2MEN1KMT2AMAPTADORA2A | |
| SCHEMBL7423428 | 0.72 | CCR2 (0.56) | ALDH1A1 | |
| SCHEMBL27837246 | 0.71 | CCR2 (0.52) | ALDH1A1MAPTP2RX4 | |
| SCHEMBL34468871 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16627883 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTCNR1CNR2HTR4 | |
| SCHEMBL11437411 | 0.69 | ALDH1A1 (0.60) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16236935 | 0.68 | MAOB (0.55) | SMN1; SMN2MEN1KMT2AALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |