Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627772 | 0.94 | RAB9A (0.47) | CNR1CNR2MAPTNPC1RAB9A | |
| SCHEMBL16627769 | 0.80 | CNR1 (0.47) | CNR1CNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16627636 | 0.80 | SMN1; SMN2 (0.51) | CNR1CNR2MAPTNPC1RAB9A | |
| SCHEMBL16627771 | 0.76 | SMN1; SMN2 (0.45) | CNR1CNR2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL16627655 | 0.75 | NPC1 (0.52) | CNR1CNR2MAPTNPC1RAB9A | |
| SCHEMBL16627834 | 0.75 | KMT2A (0.53) | CNR1CNR2MAPTSMN1; SMN2LMNA | |
| SCHEMBL16627836 | 0.73 | NR1H2 (0.42) | CNR1CNR2MAPTNPC1LMNA | |
| SCHEMBL16627684 | 0.73 | PLCG2 (0.48) | CNR1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16627643 | 0.73 | NPC1 (0.51) | CNR1CNR2MAPTNPC1RAB9A | |
| SCHEMBL16627738 | 0.73 | NPC1 (0.58) | CNR1CNR2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |