Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627829 | 0.86 | KMT2A (0.49) | KMT2APOLBMEN1LMNASMN1; SMN2 | |
| SCHEMBL16627834 | 0.85 | KMT2A (0.53) | KMT2APOLBMEN1LMNASMN1; SMN2 | |
| SCHEMBL16627581 | 0.82 | CNR1 (0.54) | KMT2AMEN1LMNAAHRSLC6A5 | |
| SCHEMBL16627830 | 0.81 | CNR1 (0.47) | KMT2APOLBMEN1SMN1; SMN2AHR | |
| SCHEMBL25474382 | 0.79 | KMT2A (0.62) | KMT2APOLBMEN1SMN1; SMN2GAA | |
| SCHEMBL16627697 | 0.77 | CNR2 (0.49) | KMT2APOLBMEN1AHRMAPT | |
| SCHEMBL5438302 | 0.76 | KMT2A (0.55) | KMT2APOLBMEN1LMNAMAPT | |
| SCHEMBL16627827 | 0.75 | AHR (0.49) | KMT2AMEN1SMN1; SMN2AHRMAPT | |
| SCHEMBL16627772 | 0.74 | RAB9A (0.47) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| SCHEMBL11053552 | 0.74 | CA1 (0.56) | KMT2APOLBMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |