Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | F12 | P00748 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397253 | 0.83 | AHR (0.85) | AHRRAB9AMEN1KMT2AF12 | |
| SCHEMBL30237030 | 0.83 | AHR (0.85) | AHRRAB9AMEN1KMT2AF12 | |
| SCHEMBL16627573 | 0.83 | MCL1 (0.46) | AHRMAOBMAOAALDH1A1TSHR | |
| SCHEMBL16627741 | 0.81 | AHR (0.61) | AHRRAB9AMEN1KMT2AF12 | |
| SCHEMBL16627820 | 0.76 | AHR (1.00) | AHRRAB9AMEN1KMT2AF12 | |
| SCHEMBL16627821 | 0.75 | AHR (0.83) | AHRRAB9AMEN1KMT2AMAOB | |
| SCHEMBL16627748 | 0.74 | AHR (0.73) | AHRRAB9AMEN1KMT2AMAOB | |
| SCHEMBL25203869 | 0.74 | AHR (0.77) | AHRRAB9ANPC1HTTALDH1A1 | |
| SCHEMBL16627752 | 0.74 | AHR (0.81) | AHRRAB9AMEN1KMT2AF12 | |
| SCHEMBL16627756 | 0.74 | AHR (1.00) | AHRRAB9AMEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |